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Table 1 Selected E2-induced splicing events

From: Interplay between estrogen receptor and AKT in Estradiol-induced alternative splicing

Gene name Reference Variant Splicing event Long form p value Fold change with E2
Caspase 7, apoptosis-related cysteine protease (CASP7), transcript variant beta, NM_033340 BM459840 ASA R 0.000 2.01
BG339524 ES R 0.000 2.20
BX458514 ES R 0.000 1.96
AU131461 ASD R 0.000 2.21
BX443602 ASD V 0.000 2.18
Axin 1 (AXIN1), transcript variant 1 NM_003502 AA954457 ES R 0.000 1.48
BU500157 ES R 0.000 1.48
Cyclin E1 (CCNE1), transcript variant 1 NM_001238 BG395682 ES R 0.000 1.41
CR601172 IR V 0.000 1.57
BE887210 ES R 0.001 1.41
Homeodomain interacting protein kinase 2 (HIPK2) NM_022740 AF326592 ASA R 0.000 1.36
Tumor necrosis factor receptor superfamily, member 12A (TNFRSF12A, FN14) NM_016639 BC064377 ES R 0.000 -1.4
Tumor necrosis factor receptor superfamily, member 10A (TNFRSF10A) NM_003844 BI029612 ASD R 0.001 -2.01
Inhibitor of DNA binding 1, dominant negative helix-loop-helix protein (ID1), transcript variant 2 NM_181353 AI767705 PIED R 0.000 -2.52
BP261920 PIED R 0.000 -2.71
Tumor necrosis factor receptor superfamily, member 6 (TNFRSF6), transcript variant 1 (FAS) NM_000043 NM_152876 ES R 0.000 1.14
Tumor necrosis factor receptor superfamily, member 6 (TNFRSF6), transcript variant 1 (FAS) NM_000043 NM_152874 ES R 0.001 -1.36
Ubiquitin-activating enzyme E1C (UBA3 homolog, yeast) (UBE1C), transcript variant 1 NM_003968 AV716795 ASA R 0.000 3.85
  1. Reference and variant transcripts with accession number in the array are shown. Longer version of the transcript in the array (reference or the variant) is also indicated. Positive number in fold change column indicates E2-induced splicing generating higher levels of the variant whereas negative number indicates repression of splicing event leading to generation of the variant. ASA, alternative splice acceptor; ASD; Alternative splice donor; ES, exon skipping; IR, intron retention; PEID, partial internal exon deletion. Additional splicing events including novel exons (NE) are in Additional file 1, Additional file 2, Additional file 3.