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Table 1 Enriched GO categories of chromosome 21 up-regulated genes

From: Validation of microarray data in human lymphoblasts shows a role of the ubiquitin-proteasome system and NF-kB in the pathogenesis of Down syndrome

     GO term Genes %* p-value FE
ATPase activity, coupled to transmembrane movement of substances ATP5O 6.2 0.005 11.3
ATP5J    
ABCG1    
Cofactor metabolic process SOD1 6.2 0.029 5.8
  FTCD    
  PDXK    
  CRYZL1    
Regulation of cholesterol biosynthetic process ABCG1 3.1 0.031 62.2
SOD1    
Oxidative phosphorylation ATP5O 4.7 0.04 9.2
  ATP5J    
  NDUFV3    
  1. FE fold enrichment, *% of genes in category.