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Table 1 Enriched GO categories of chromosome 21 up-regulated genes

From: Validation of microarray data in human lymphoblasts shows a role of the ubiquitin-proteasome system and NF-kB in the pathogenesis of Down syndrome

     GO term

Genes

%*

p-value

FE

ATPase activity, coupled to transmembrane movement of substances

ATP5O

6.2

0.005

11.3

ATP5J

   

ABCG1

   

Cofactor metabolic process

SOD1

6.2

0.029

5.8

 

FTCD

   
 

PDXK

   
 

CRYZL1

   

Regulation of cholesterol biosynthetic process

ABCG1

3.1

0.031

62.2

SOD1

   

Oxidative phosphorylation

ATP5O

4.7

0.04

9.2

 

ATP5J

   
 

NDUFV3

   
  1. FE fold enrichment, *% of genes in category.