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Table 2 Enriched pathways of chromosome 21 up-regulated genes

From: Validation of microarray data in human lymphoblasts shows a role of the ubiquitin-proteasome system and NF-kB in the pathogenesis of Down syndrome

  Pathway term

Genes

%

p-value

FE

Parkinson’s disease

ATP5O

6.2

0.010

8.3

 

ATP5J

   
 

NDUFV3

   
 

UBC6/7

   

Alzheimer’s disease

ATP5O

6.2

0.023

6.1

 

ATP5J

   
 

NDUFV3

   
 

BACE

   

Huntington’s disease

ATP5O

6.2

0.030

5.5

 

ATP5J

   
 

NDUFV3

   
 

SOD1

   
  1. FE fold enrichment.
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BMC Medical Genomics

ISSN: 1755-8794

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