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Table 2 Enriched pathways of chromosome 21 up-regulated genes

From: Validation of microarray data in human lymphoblasts shows a role of the ubiquitin-proteasome system and NF-kB in the pathogenesis of Down syndrome

  Pathway term Genes % p-value FE
Parkinson’s disease ATP5O 6.2 0.010 8.3
  ATP5J    
  NDUFV3    
  UBC6/7    
Alzheimer’s disease ATP5O 6.2 0.023 6.1
  ATP5J    
  NDUFV3    
  BACE    
Huntington’s disease ATP5O 6.2 0.030 5.5
  ATP5J    
  NDUFV3    
  SOD1    
  1. FE fold enrichment.