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Table 7 Enriched GO categories of the up-regulated genes (p < 0.01), sorted by p-value

From: Validation of microarray data in human lymphoblasts shows a role of the ubiquitin-proteasome system and NF-kB in the pathogenesis of Down syndrome

Biological process     GO term N. of genes %* p-value FE
Transport and localization calcium ion transport 5 8.3 0.001 10.6
transmembrane transport 7 11.7 0.01 3.7
  metal ion transport 6 10.0 0.016 3.9
  localization 17 28.3 0.022 1.7
  cation transport 6 10.0 0.032 3.3
  transport 15 25.0 0.034 1.7
  ion transport 7 11.7 0.035 2.8
  establishment of localization 15 25.0 0.037 1.7
Development cellular developmental process 14 23.3 0.002 2.5
  anatomical structure development 17 28.3 0.004 2.0
  cell differentiation 13 21.7 0.005 2.4
  system development 16 26.7 0.005 2.1
  multicellular organismal development 17 28.3 0.015 1.8
  organ development 12 20.0 0.021 2.1
  1. FE fold enrichment, *% of genes in category.