Whole transcriptome sequencing identifies tumor-specific mutations in human oral squamous cell carcinoma

BMC Medical Genomics

Table 3 Enriched GO and pathway categories

Term	Description	Adjusted P	Category^a	GeneSet^b
GO:0022843	voltage-gated cation channel activity	0.019	MF	SMG
GO:0031224	intrinsic to membrane	0.001	CC	SMG
GO:0016021	integral to membrane	0.001	CC	SMG
GO:0005887	integral to plasma membrane	0.009	CC	SMG
GO:0031226	intrinsic to plasma membrane	0.011	CC	SMG
HSA04080	Neuroactive ligand-receptor interaction	0.055	KEGG	SMG
HSA04514	Cell adhesion molecules (CAMs)	0.052	KEGG	SMG
HSA04610	Complement and coagulation cascades	0.052	KEGG	SMG
HSA00100	Steroid biosynthesis	0.110	KEGG	TDG
HSA03010	Ribosome	0.110	KEGG	TDG
HSA04960	Aldosterone-regulated sodium reabsorption	0.110	KEGG	TDG

^a MF molecular function term in GO, CC cellular component term in GO, KEGG KEGG pathway terms.
^b SMG significantly mutated genes, TDG tumor-specific disruptive genes (see main text for details).

ISSN: 1755-8794