Table 2 Distributions of allele and genotype frequencies of NOS SNPs in children with and without OSA

NOS1

rs9658535

A/G

n=477

n=128

0.04

0.26

0.07–1.06

n

%

n

%

AA

421

88

116

91

GA

52

11

8

6

GG

4

1

4

3

Allele A

894

94

240

94

Allele G

60

6

16

6

rs7960451

C/T

n=480

n=128

0.02

0.21

0.05–0.78

n

%

n

%

CC

417

87

112

87

TC

59

12

11

9

TT

4

1

5

4

Allele C

893

93

235

92

Allele T

67

7

21

8

rs4767524

C/G

n=478

n=128

0.04

0.71

0.43–1.15

n

%

n

%

CC

160

33

52

41

GC

242

51

49

38

GG

76

16

27

21

Allele C

562

59

153

60

Allele G

394

41

103

40

rs2293050

A/G

n=478

n=128

0.0002

1.59

1.04–2.43

n

%

n

%

AA

82

17

13

10

AG

208

44

78

61

GG

188

39

37

29

Allele A

372

39

104

41

Allele G

584

61

152

59

rs10744891

G/T

n=465

n=121

0.004

1.72

0.90–3.28

n

%

n

%

GG

185

40

35

29

TG

206

44

74

61

TT

74

16

12

10

Allele G

576

62

144

60

Allele T

354

38

98

40

rs9658354

A/T

n=478

n=126

0.001

1.74

1.13–2.68

n

%

n

%

AA

80

17

13

10

AT

211

44

79

63

TT

187

39

34

27

Allele A

371

39

105

42

Allele T

585

61

147

58

rs2139733

A/T

n=478

n=128

0.002

1.65

1.08–2.52

n

%

n

%

AA

77

16

13

10

AT

209

44

78

61

TT

192

40

37

29

Allele A

363

38

104

41

Allele T

593

62

152

59

rs1520810

A/T

n=478

n=127

0.03

0.86

0.38–1.94

n

%

n

%

AA

263

55

85

67

TA

189

40

34

27

TT

26

5

8

6

Allele A

715

75

204

80

Allele T

241

25

50

20

rs471871

A/T

n=478

n=127

0.01

0.55

0.37–0.82

n

%

n

%

AA

51

11

13

10

AT

212

44

38

30

TT

215

45

76

60

Allele A

314

33

64

25

Allele T

642

67

190

75

rs528558

A/G

n=479

n=128

0.03

0.61

0.41–0.92

n

%

n

%

AA

26

5

8

6

AG

191

40

35

27

GG

262

55

85

66

Allele A

243

25

51

20

Allele G

715

75

205

80

rs816296

A/C

n=478

n=127

0.04

0.58

0.38–0.89

n

%

n

%

AA

24

5

4

3

AC

174

36

33

26

CC

280

59

90

71

Allele A

222

23

41

16

Allele C

734

77

213

84

rs579604

C/T

n=479

n=128

0.04

N/A

N/A

n

%

n

%

CC

310

65

96

75

TC

158

33

32

25

TT

11

2

0

0

Allele C

778

81

224

88

Allele T

180

19

32

12

rs1552227

C/T

n=479

n=128

0.02

0.47

0.22–0.97

n

%

n

%

CC

294

61

63

49

TC

163

34

53

42

TT

22

5

12

9

Allele C

751

78

179

70

Allele T

207

22

77

30

rs17509231

C/T

n=478

n=128

0.02

0.40

0.07–2.41

n

%

n

%

CC

395

83

92

72

TC

80

17

34

26

TT

3

0

2

2

Allele C

870

91

218

85

Allele T

86

9

38

15

rs3782221

A/G

n=477

n=128

0.02

0.61

0.41–0.90

n

%

n

%

AA

36

7

4

3

AG

213

45

47

37

GG

228

48

77

60

Allele A

285

30

55

21

Allele G

669

70

201

79

NOS3

rs1800780

A/G

n=470

n=126

0.05

0.71

0.47–1.09

n

%

n

%

AA

103

22

16

13

AG

240

51

67

53

GG

127

27

43

34

Allele A

446

47

99

39

Allele G

494

53

153

61