Table 3 Distributions of allele and genotype frequencies of EDN SNPs in children with and without OSA

EDN1

rs1014505

n=478

n=127

<0.001

1.28

0.85-1.92

C/G

n

%

n

%

CC

62

13

36

29

CG

215

45

45

35

GG

201

42

46

36

Allele C

339

35

117

46

Allele G

617

65

137

54

rs2070698

C/T

n=480

n=128

0.04

1.73

1.07-2.79

n

%

n

%

CC

102

21

37

29

CT

236

49

66

52

TT

142

30

25

19

Allele C

440

46

140

55

Allele T

520

54

116

45

rs2248580

n=478

n=128

0.02

1.07

0.72-1.59

A/C

n

%

n

%

AA

60

12

28

22

AC

208

44

46

36

CC

210

44

54

42

Allele A

328

34

102

40

Allele C

628

66

154

60

rs2070699

G/T

n=479

n=128

0.002

0.42

0.25-0.69

n

%

n

%

GG

213

45

55

43

TG

216

45

45

35

TT

50

10

28

22

Allele G

642

67

155

61

Allele T

316

33

101

39

EDN2

rs11210273

C/T

n=478

n=128

0.02

NA

NA

n

%

n

%

CC

411

86

105

82

TC

67

14

21

16

TT

0

0

2

2

Allele C

889

93

231

90

Allele T

67

7

25

10

EDN3

rs6064764

C/T

n=479

n=127

0.02

0.90

0.60-1.34

n

%

n

%

CC

27

6

15

12

CT

174

36

35

27

TT

278

58

77

61

Allele C

228

24

65

26

Allele T

730

76

189

74