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Table 1 KEGG pathway enrichment analysis for mRNA and miRNA genes differentially expressed in tumor and normal derived pancreatic cell lines

From: An integrated transcriptome and epigenome analysis identifies a novel candidate gene for pancreatic cancer

KEGG pathway ID

KEGG pathway name

P-value

FDR

# of genes

05200

Pathways in cancer

5.40 × 10-06

1.15 × 10-04

69

04510

Focal adhesion

1.05 × 10-11

1.12 × 10-09

61

04512

ECM-receptor interaction

1.11 × 10-14

2.37 × 10-12

36

04060

Cytokine-cytokine receptor interaction

3.43 × 10-07

1.22 × 10-05

36

04310

Wnt signaling pathway

6.26 × 10-05

8.75 × 10-04

36

04360

Axon guidance

3.82 × 10-06

9.05 × 10-05

33

04514

Cell adhesion molecules (CAMs)

2.27 × 10-08

9.67 × 10-07

29

04020

Calcium signaling pathway

1.47 × 10-05

2.61 × 10-04

29

04080

Neuroactive ligand-receptor interaction

1.78 × 10-08

9.47 × 10-07

26

05412

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

1.44 × 10-08

9.47 × 10-07

24

05414

Dilated cardiomyopathy

3.82 × 10-06

9.05 × 10-05

22

05410

Hypertrophic cardiomyopathy (HCM)

2.64 × 10-06

8.02 × 10-05

21

04640

Hematopoietic cell lineage

1.47 × 10-05

2.61 × 10-04

16

05217

Basal cell carcinoma

6.58 × 10-05

8.75 × 10-04

15

04610

Complement and coagulation cascades

1.01 × 10-04

1.27 × 10-03

10

  1. KEGG pathway ID numbers are listed and statistical significance is shown by P values and FDR values.