Figure 2From: Genomic pathway analysis reveals that EZH2 and HDAC4 represent mutually exclusive epigenetic pathways across human cancers Epigenetic pathway activation across cancer types. Epigenetic signatures were projected into the CCLE (A EZH2 signature, B HDAC4 signature), GSK cell lines (C EZH2 signature, D HDAC4 signature), and a dataset of primary tumors from GSE5364 (E EZH2 signature, F HDAC4 signature). Only tumor types represented in both the CCLE and GSK sets are shown. All x-axes are in the same order. Relative activation between different cancer types of each pathway are similar across the datasets.Back to article page