BMC Medical Genomics

Table 2 Top correlations between genes and CPE in each brain region

From: Systems analysis of human brain gene expression: mechanisms for HIV-associated neurocognitive impairment and common pathways with Alzheimer’s disease

Frontal cortex			Basal ganglia			White matter
Gene name	R	P-value*	Gene name	R	P-value*	Gene name	R	P-value*
WBSCR16	0.82	0.0003	LOC730496	0.82	0.0003	TMEM57	−0.81	0.0006
MYST1	0.82	0.0004	CA13	0.82	0.0003	NFIC	0.80	0.0006
RPS6KB2	0.82	0.0004	CLEC14A	0.81	0.0004	KIAA0515	0.79	0.0007
ZNF26	0.81	0.0004	C18orf17	0.78	0.0010	CIDEB	0.79	0.0007
DCAKD	−0.79	0.0008	OSBPL6	−0.77	0.0012	RDH11	−0.79	0.0008
LYPLA2	0.78	0.0009	MRAS	0.77	0.0012	HMHB1	−0.79	0.0009
NME3	0.78	0.0010	SSR3	0.77	0.0012	VPS13D	0.78	0.0011
SLC10A2	0.76	0.0015	FUT2	0.77	0.0012	TAF5L	0.77	0.0012
TRIM31	0.76	0.0015	EHHADH	0.76	0.0014	TNPO3	0.77	0.0014
			MOSPD1	−0.76	0.0015	FLJ45803	0.76	0.0017
			SIKE	0.76	0.0016	C6orf113	−0.76	0.0018
			TMEM67	−0.76	0.0016	C19orf43	0.75	0.0018
			LASS4	0.76	0.0017	SH3GLP3	0.75	0.0018
			AGPAT6	0.76	0.0017
			CCDC100	0.76	0.0017
			ACVR2B	0.75	0.0018
			SREBF2	0.75	0.0018

* p-values shown are not corrected for multiple comparisons.

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