Genes down-regulated with impairment in both AD and HIV | ||||||
---|---|---|---|---|---|---|
Gene Category | List Hits | List Total | Pop Hits | Pop Total | EASE score | Bonferroni |
Cytoplasm | 175 | 259 | 2277 | 4968 | 5.62E-13 | 1.40E-09 |
Energy pathways | 26 | 259 | 128 | 5016 | 4.16E-09 | 1.04E-05 |
Mitochondrion | 48 | 259 | 396 | 4968 | 3.27E-08 | 8.15E-05 |
Tricarboxylic acid cycle | 10 | 259 | 20 | 5016 | 2.24E-07 | 5.58E-04 |
Transit peptide | 28 | 217 | 184 | 4007 | 1.14E-06 | 2.85E-03 |
Synaptic vesicle | 10 | 259 | 30 | 4968 | 1.31E-05 | 3.26E-02 |
Genes up-regulated with impairment in both AD and HIV | ||||||
Cell differentiation | 10 | 131 | 90 | 5016 | 4.79E-13 | 1.40E-09 |
Activator | 11 | 105 | 131 | 4007 | 1.89E-03 | 1.00E + 00 |
Repeat | 42 | 105 | 1051 | 4007 | 1.98E-03 | 1.00E + 00 |
Cell communication | 50 | 131 | 1363 | 5016 | 5.20E-03 | 1.00E + 00 |
Regulation of transcription | 32 | 131 | 762 | 5016 | 5.70E-03 | 1.00E + 00 |
Phosphorylation | 26 | 105 | 582 | 4007 | 6.18E-03 | 1.00E + 00 |