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Table 6 Brain cell-specific alterations common to AD and HIV

From: Systems analysis of human brain gene expression: mechanisms for HIV-associated neurocognitive impairment and common pathways with Alzheimer’s disease

Direction of change

Cell type enrichment

Bonferroni

Down with impairment

Neuron (probable)*

3.68E-12

Down with impairment

Neuron (definite)*

1.13E-04

Up with impairment

Astrocyte (probable)

3.34E-12

  1. * Definite (10+ fold) and probable (1.5+ fold) enrichment from Cahoy et al. [53].
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BMC Medical Genomics

ISSN: 1755-8794

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