Table 1 Selected gene sets associated with clustering-defined groups of clones of melanoma cell line LM-MEL-62
Gene set description | NES | FDR | MSigDB ID |
|---|---|---|---|
Genes sets enriched in Clones 4,7,8,9 | |||
Up-regulated in melanoma patients with distant metastasis within 4 years | 2.60 | 0.000 | M6387 |
DNA repair and replication genes up-regulated in melanoma patients who relapsed | 2.46 | 0.000 | M2431 |
Up-regulated in metastases to primary melanomas | 2.14 | 0.000 | M5740 |
Genes sets enriched in Clones 1,5,6 | |||
Genes up-regulated in fibroblasts after interferon alpha treatment | 2.10 | 0.000 | M9221 |
Tumor necrosis factor pathway | 1.95 | 0.003 | M18030 |
NOTCH signaling | 1.89 | 0.006 | M7946 |
Genes sets enriched in 2,3,10 | |||
Genes up-regulated in MET over-expressing colon cancer xenografts | 2.23 | 0.000 | M3231 |
Genes involved in G beta:gamma signaling through PI3Kgamma | 1.79 | 0.046 | M14301 |