Skip to main content

Table 4 The genes showing the highest down-regulation of corpus expression in patients with corpus atrophy (ranked by regression coefficients)

From: Transcriptome signatures in Helicobacter pylori-infected mucosa identifies acidic mammalian chitinase loss as a corpus atrophy marker

ID

Symbol

Description

Corpus

Antrum

Fold changeb

Clusterc

Ba

R 2

Ba

R 2

Hp-

Hp+

Atr

ILMN_25453

AMCase

chitinase, acidic, transcript variant 1

-3.66

0.69

-0.74

0.04

93

97

2

C4

ILMN_12978

MRGPRD

MAS-related GPR, member D

-3.32

0.71

-0.59

-0.04

103

100

2

C4

ILMN_27134

CHRD

chordin, transcript variant 2

-3.25

0.69

-0.87

0.13

69

65

3

C4

ILMN_24872

AMCase

chitinase, acidic, transcript variant 2

-3.24

0.69

-0.65

0.11

37

31

1

C4

ILMN_16471

ATP4A

ATPase, H+/K + exchanging, alpha polypeptide

-3.03

0.87

-0.78

0.10

46

37

2

C4

ILMN_21851

AQP4

aquaporin 4, transcript variant b

-2.80

0.85

-0.74

0.14

27

25

2

C4

ILMN_23805

AGXT2L1

alanine-glyoxylate aminotransferase 2-like 1

-2.77

0.93

-0.48

0.10

27

9

1

C4

ILMN_11251

PTGER3

prostaglandin E receptor 3, transcript variant 9

-2.67

0.85

-0.58

0.07

27

15

2

C4

ILMN_12353

ATP4B

ATPase, H+/K + exchanging, beta polypeptide

-2.60

0.70

-1.28

0.13

49

46

8

C4

ILMN_11182

FGA

fibrinogen alpha chain , transcript variant alpha

-2.40

0.90

-0.54

0.10

20

12

2

C4

ILMN_13882

FGB

fibrinogen beta chain

-2.39

0.89

-0.26

-0.03

31

3

2

C4

ILMN_17569

OGG1

8-oxoguanine DNA glycosylase, transcript variant 1b

-2.34

0.66

-0.30

-0.02

17

17

1

C4

ILMN_10755

CKB

creatine kinase, brain

-2.29

0.88

-0.76

0.39

14

9

2

C4

ILMN_13759

GPR30

G protein-coupled receptor 30, transcript variant 1

-2.28

0.73

-0.51

0.08

19

12

2

C4

ILMN_20448

CPA2

carboxypeptidase A2 (pancreatic)

-2.21

0.65

-0.38

-0.09

47

26

4

nc

ILMN_20479

SIGLEC11

sialic acid binding Ig-like lectin 11

-2.20

0.91

-0.38

0.04

13

8

1

C4

ILMN_23656

SH3GL2

SH3-domain GRB2-like 2

-2.18

0.78

-0.26

-0.07

17

12

1

C4

ILMN_28182

FLJ35258

hypothetical protein 284297

-2.18

0.76

-0.38

0.47

16

7

1

C4

ILMN_28694

CDH2

cadherin 2, type 1, N-cadherin (neuronal)

-2.17

0.86

-0.20

-0.06

16

7

1

C4

ILMN_5239

FNDC5

fibronectin type III domain containing 5

-2.13

0.88

-0.37

0.29

12

4

1

C4

ILMN_19137

MFSD4

major facilitator superfamily domain containing 4

-2.09

0.86

-0.49

0.16

13

9

1

C4

ILMN_6662

TRIM50

tripartite motif-containing 50

-2.05

0.84

-0.24

-0.07

16

13

1

C4

ILMN_16766

ZNF533

zinc finger protein 533

-2.04

0.85

-0.37

0.07

12

7

1

C4

ILMN_27352

CLIC6

chloride intracellular channel 6

-2.02

0.64

-0.40

-0.05

20

11

2

nc

ILMN_4712

SERPINA5

serpin peptidase inhibitor, clade A, member 5

-2.02

0.88

-0.40

-0.09

14

1

2

C4

ILMN_15602

CLCNKA

chloride channel Ka

-2.01

0.88

-0.28

-0.06

14

8

1

C4

ILMN_19114

DNER

delta-notch-like EGF repeat-containing transmembrane

-2.01

0.86

-0.54

0.22

12

5

2

C4

  1. The goodness of fits were also reported by R 2;
  2. aRegression coefficient. Linear regression was performed along the three patient groups (Hp-, Hp + and Atr).
  3. bCorpus vs. antrum gene expression fold changes of the individual patient groups.
  4. cThe result from clustering analysis; nc = not included in clustering analysis.
Back to article page

BMC Medical Genomics

ISSN: 1755-8794

Contact us