Table 2 Results of gene expression data
From: Assessment of inflammatory resilience in healthy subjects using dietary lipid and glucose challenges
Genes significantly changed in the control challenge compared to baseline | ||||||||
|---|---|---|---|---|---|---|---|---|
# | Name | Symbol | GeneID | 0vs2 h | 0vs6 h | p | ||
1 | ABCA1 | ABCA1 | 19 | 1,33 | 1,40 | 0.001 | ||
2 | FLaP | ALOX5AP | 241 | 1,38 | 1,12 | 0.023 | ||
3 | CXCR2 = IL-8RB | CXCR2 | 3579 | 1,26 | 1,09 | 0.042 | ||
4 | IL1RA | IL1RN | 3557 | 1,19 | 1,17 | 0.009 | ||
5 | NLRP3 | NLRP3 | 114548 | 1,12 | 1,08 | 0.011 | ||
6 | PPARG | PPARG | 5468 | -1,33 | -1,11 | 0.004 | ||
7 | PTX3 | PTX3 | 5806 | -1,37 | -1,50 | 0.013 | ||
8 | TLR2 (LPS) | TLR2 | 7097 | -1,13 | -1,21 | 0.030 | ||
9 | TNF-α | TNF | 7124 | 1,18 | 1,18 | 0.025 | ||
10 | CCR6 | CCR6 | 1235 | 1,02 | 1,23 | 0.017 | ||
11 | DUSP2 | DUSP2 | 1844 | -1,64 | -1,55 | 0.006 | ||
12 | FPR2/ALX | FFRA1 | 2358 | 1,05 | -1,02 | 0.041 | ||
13 | ERK | MAPK1 | 5594 | 1,11 | 1,05 | 0.022 | ||
Genes significantly changed in OGTT compared to control challenge | ||||||||
# | Name | Symbol | GeneId | p | OGTT | Control | ||
0vs2 h | 0vs6 h | 0vs2 h | 0vs6 h | |||||
1 | CXCR3 | CXCR3 | 2833 | 0.009 | 1,11 | -1,07 | -1,04 | 1,23 |
2 | IL10RA | IL10RA | 3587 | 0.016 | -1,14 | -1,26 | -1,12 | -1,06 |
3 | INSIG1 (insulin induced gene 1) | INSIG1 | 3638 | 0.031 | -1,02 | -1,06 | -1,04 | 1,01 |
4 | pyruvate dehydrogenase kinase 4 | PDK4 | 5166 | 0.009 | -3,11 | 1,66 | 1,11 | 1,37 |
5 | ITGB1 | ITGB1 | 3688 | 0.047 | -1,09 | -1,10 | -1,06 | 1,09 |
6 | lipocalin-2 | LCN2 | 3934 | 0.0002 | -1,07 | -1,29 | 1,10 | 1,03 |
7 | carnitine-acylcarnitine translocase | SLC25A20 | 788 | 0.031 | -1.31 | 1,26 | 1,08 | 1,11 |
Genes significantly changed in OLTT compared to control challenge | ||||||||
# | Name | Symbol | GeneId | p | OLTT | Control | ||
0vs2 h | 0vs6 h | 0vs2 h | 0vs6 h | |||||
1 | acyl-Coenzyme A dehydrogenase | ACADVL | 37 | 0.029 | -1,18 | 1,37 | 1,01 | 1,12 |
2 | CYP4F3 | CYP4F3 | 4051 | 0.012 | 1,11 | 1,20 | 1,14 | 1,12 |
3 | ERK | MAPK1 | 5594 | 0.035 | -1,08 | -1,09 | 1,11 | 1,05 |
Genes significantly changed in OG + LTT compared to control challenge | ||||||||
# | Name | Symbol | GeneId | p | OG + LTT | Control | ||
0vs2 h | 0vs6 h | 0vs2 h | 0vs6 h | |||||
1 | CCR2 | CCR2 | 729230 | 0.021 | 1,02 | -1,09 | -1,11 | -1,02 |
2 | Mgl CD301 | CLEC10A | 10462 | 0.002 | -1,17 | -1,01 | -1,09 | 1,18 |
3 | ITGAL CD11a | ITGAL | 3683 | 0.041 | -1,10 | -1,10 | 1,02 | 1,05 |
5 | IL-18 | IL18 | 3606 | 0.029 | -1,01 | 1,12 | -1,18 | -1,14 |
6 | CD162 - P-selectin ligand | SELPLG | 6404 | 0.027 | 1,05 | -1,09 | 1,07 | -1,05 |
7 | carnitine-acylcarnitine translocase | SLC25A20 | 788 | 0.041 | 1,08 | 1,11 | -1,25 | 1,22 |