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Table 1 RUNX2 and VEGFA protein expression level and their correlation with clinical pathologic factors

From: Correlation of WWOX, RUNX2 and VEGFA protein expression in human osteosarcoma

Characteristics RUNX2 VEGFA
  - + ++ +++ Pvalue - + ++ +++ Pvalue
Sex
Male (26) 15 4 1 6 0.435 10 5 4 7 0.012*
Female (28) 13 9 2 4 3 17 2 6
Age groups
≤15 y (14) 8 3 0 3 0.027* 4 6 0 4 0.730
15–20 y (22) 11 7 2 2 5 9 2 6
21–30 y (9) 5 2 0 2 1 4 2 2
31–40 y (1) 0 0 1 0 1 0 0 0
>40 y (8) 4 1 0 3 2 3 2 1
PTNM stage
I stage (4) 2 1 0 1 0.906 0 3 1 0 0.168
II stage (18) 8 4 3 3 5 5 1 7
III stage (2) 2 0 0 0 0 1 1 0
IV stage (1) 1 0 0 0 1 0 0 0
Recurrence
No (47) 26 11 2 8 0.484 13 20 4 10 0.132
Yes (7) 2 2 1 2 0 2 2 3
Metastasis
No (35) 19 8 2 6 0.951 11 14 3 7 0.351
Yes (11) 5 3 1 2 1 4 2 4
Disease free survival (mean months ± sd) Log Rankχ2 = 1.331 (60.238 ± 7.881) 0.722 Log Rankχ2 = 6.277 (60.238 ± 7.881) 0.099
Overall survival (mean months ± sd) Log Rankχ2 = 0.984 0.805 Log Rankχ2 = 0.471 (70.903 ± 6.737) 0.925
  1. *Significantly different P < 0.05.