Skip to main content

Table 2 Comparisons of BRIDGE with CIPHER and ENDEAVOUR

From: Integrating human omics data to prioritize candidate genes

  Artificial linkage interval Random control
  TOP AUC FE MRR TOP AUC FE MRR
CIPHER1 47.41% 86.08% 51.66 16.94% 42.07% 82.23% 42.07 18.05%
BRIDGE1 62.47% 90.86% 68.09 8.90% 57.42% 90.78% 57.42 8.34%
ENDEAVOUR2 45.80% 91.89% 49.92 7.79% 44.10% 92.03% 44.10 11.27%
BRIDGE2 66.15% 94.17% 72.10 6.73% 63.50% 93.85% 63.50 6.95%
  1. 1CIPHER and BRIDGE are evaluated using the 1,428 associations between 1,126 diseases and 938 genes. 2ENDEAVOUR and BRIDGE are evaluated using the 470 associations between 168 diseases and 375 genes.