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Table 2 Comparisons of BRIDGE with CIPHER and ENDEAVOUR

From: Integrating human omics data to prioritize candidate genes

 

Artificial linkage interval

Random control

 

TOP

AUC

FE

MRR

TOP

AUC

FE

MRR

CIPHER1

47.41%

86.08%

51.66

16.94%

42.07%

82.23%

42.07

18.05%

BRIDGE1

62.47%

90.86%

68.09

8.90%

57.42%

90.78%

57.42

8.34%

ENDEAVOUR2

45.80%

91.89%

49.92

7.79%

44.10%

92.03%

44.10

11.27%

BRIDGE2

66.15%

94.17%

72.10

6.73%

63.50%

93.85%

63.50

6.95%

  1. 1CIPHER and BRIDGE are evaluated using the 1,428 associations between 1,126 diseases and 938 genes. 2ENDEAVOUR and BRIDGE are evaluated using the 470 associations between 168 diseases and 375 genes.