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Table 1 Significantly over-represented gene ontology biological processes associated with differentially expressed genes in the colon of mice supplemented with adequate levels of selenium and folate post-weaning (n = 6 per treatment)

From: Post-weaning selenium and folate supplementation affects gene and protein expression and global DNA methylation in mice fed high-fat diets

Term GOid Gene name Systematic name Description Fold change P value
Organelle organization GO:0006996 Top2a NM_011623 Mus musculus topoisomerase (DNA) II alpha −1.7 0.006
   Stx6 NM_021433 Mus musculus syntaxin 6 −1.6 0.003
   Col4a3bp NM_023420 Mus musculus procollagen, type IV, alpha 3 (Goodpasture antigen) binding protein −1.5 0.004
   Pom121 NM_148932 Mus musculus nuclear pore membrane protein 121 −1.7 0.004
   Shprh AK037266 Mus musculus 16 days neonate thymus −1.6 0.003
Lipid homeostasis GO:0055088 Col4a3bp NM_023420 Mus musculus procollagen, type IV, alpha 3 (Goodpasture antigen) binding protein −1.5 0.004
   Plscr3 NM_023564 Mus musculus phospholipid scramblase 3 −1.6 0.007
Cellular component organization GO:0016043 Nov NM_010930 Mus musculus nephroblastoma overexpressed gene −1.7 0.005
   Top2a NM_011623 Mus musculus topoisomerase (DNA) II alpha −1.7 0.006
   Stx6 NM_021433 Mus musculus syntaxin 6 −1.6 0.003
   Col4a3bp NM_023420 Mus musculus procollagen, type IV, alpha 3 (Goodpasture antigen) binding protein −1.5 0.004
   Pom121 NM_148932 Mus musculus nuclear pore membrane protein 121 −1.7 0.004
   Shprh AK037266 Mus musculus 16 days neonate thymus −1.6 0.003
Nuclear pore organization GO:0006999 Pom121 NM_148932 Mus musculus nuclear pore membrane protein 121 −1.7 0.004
Cellular process GO:0009987 Heph NM_181273 Mus musculus hephaestin, transcript variant 2 −1.5 0.001
   Mef2a NM_001033713 Mus musculus myocyte enhancer factor 2A −1.6 0.001
   Nov NM_010930 Mus musculus nephroblastoma overexpressed gene −1.7 0.005
   Rora AK087905 Mus musculus 2 days pregnant adult female ovary −1.8 0.001
   Top2a NM_011623 Mus musculus topoisomerase (DNA) II alpha −1.7 0.006
   Mtmr1 NM_016985 Mus musculus myotubularin related protein 1 −1.6 0.008
   Stx6 NM_021433 Mus musculus syntaxin 6 −1.6 0.003
   Col4a3bp NM_023420 Mus musculus procollagen, type IV, alpha 3 (Goodpasture antigen) binding protein −1.5 0.004
   Pom121 NM_148932 Mus musculus nuclear pore membrane protein 121 −1.7 0.004
   Shprh AK037266 Mus musculus 16 days neonate thymus −1.6 0.003
   Podxl2 NM_176973 Mus musculus podocalyxin-like 2 −1.6 0.005
DNA packaging GO:0006323 Top2a NM_011623 Mus musculus topoisomerase (DNA) II alpha −1.7 0.006
   Shprh AK037266 Mus musculus 16 days neonate thymus −1.6 0.003
DNA conformation change GO:0071103 Top2a NM_011623 Mus musculus topoisomerase (DNA) II alpha −1.7 0.006
   Shprh AK037266 Mus musculus 16 days neonate thymus −1.6 0.003
DNA metabolic process GO:0006259 Top2a NM_011623 Mus musculus topoisomerase (DNA) II alpha −1.7 0.006
   Shprh AK037266 Mus musculus 16 days neonate thymus −1.6 0.003
  1. A positive fold change indicates that supplementation increased the expression of the gene.