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Table 2 Heritability and correlations with age and sex of methylation status near FABP3 start codon

From: Fatty acid binding protein 3 (fabp3) is associated with insulin, lipids and cardiovascular phenotypes of the metabolic syndrome through epigenetic modifications in a northern european family population

CpG site Heritability ±SE Pheritability β±SEage Page Variance explained age β±SEsex Psex Variance explained sex
FABP3_1 0.21 ± 0.07 2.85E-05 1.70E-04 ± 1.00E-04 1.03E-01 2.99E-03 1.90E-03 ± 3.50E-03 5.87E-01 2.19E-04
FABP3_2 0.05 ± 0.07 1.89E-01 1.60E-04 ± 4.90E-05 1.64E-03 1.03E-02 −7.30E-04 ± 1.60E-03 6.59E-01 1.98E-04
FABP3_3 0.09 ± 0.08 1.11E-01 1.50E-04 ± 6.20E-05 1.32E-02 1.41E-02 4.60E-03 ± 2.00E-03 2.34E-02 5.55E-03
FABP3_4 0.18 ± 0.08 4.39E-03 4.00E-05 ± 5.00E-05 4.11E-01 1.27E-03 2.70E-03 ± 1.60E-03 8.93E-02 3.10E-03
FABP3_5 0.15 ± 0.07 7.38E-03 1.10E-04 ± 3.20E-05 7.44E-04 1.41E-02 5.40E-04 ± 1.00E-03 6.06E-01 7.51E-05
FABP3_6/7 0.17 ± 0.08 5.15E-03 1.20E-04 ± 3.20E-05 1.09E-04 1.52E-02 2.50E-04 ± 1.10E-03 8.11E-01 2.61E-05
FABP3_8 0.17 ± 0.08 3.23E-03 −2.00E-05 ± 9.80E-05 8.35E-01 3.09E-04 6.20E-03 ± 3.20E-03 5.23E-02 3.44E-03
FABP3_9 0.48± 0.08 4.53E-17 2.90E-04 ± 7.10E-05 3.95E-05 2.09E-02 −7.60E-04 ± 2.40E-03 7.48E-01 1.31E-04
FABP3_10/11/12 0.19 ± 0.09 4.40E-03 2.80E-04 ± 6.80E-05 5.77E-05 2.05E-02 6.00E-03 ± 2.20E-03 6.55E-03 7.31E-03
FABP3_13 0.46 ± 0.10 1.06E-09 2.20E-04 ± 1.10E-04 3.75E-02 8.40E-03 3.90E-03 ± 3.50E-03 2.66E-01 1.58E-03
FABP3_14 0.48 ± 0.10 2.41E-09 2.80E-04 ± 1.30E-04 3.51E-02 7.52E-03 1.30E-02 ± 4.40E-03 2.50E-03 1.11E-02
FABP3_15 0.15 ± 0.07 3.92E-03 −2.80E-04 ± 1.40E-04 4.77E-02 4.15E-03 4.50E-03 ± 4.60E-03 3.34E-01 9.95E-04
FABP3_16 0.32 ± 0.10 1.90E-05 2.30E-04 ± 8.70E-05 8.20E-03 1.04E-02 6.30E-03 ± 2.80E-03 2.72E-02 5.63E-03
FABP3_17/18 0.03 ± 0.06 2.80E-01 1.30E-04 ± 1.40E-04 3.49E-01 9.21E-04 7.60E-03 ± 4.70E-03 1.03E-01 2.78E-03
FABP3_19 0.26 ± 0.09 5.76E-05 −3.30E-04 ± 1.10E-04 2.97E-03 5.46E-03 1.30E-02 ± 3.60E-03 3.88E-04 1.16E-02
FABP3_20 0.41 ± 0.09 4.52E-09 1.00E-05 ± 9.30E-05 8.79E-01 2.61E-05 8.10E-03 ± 3.10E-03 8.91E-03 3.88E-03
FABP3_21/22 0.14± 0.08 2.15E-02 −7.00E-05 ± 1.60E-04 6.34E-01 5.56E-04 −5.50E-03 ± 5.40E-03 3.06E-01 2.50E-03
FABP3_AVG 0.22 ± 0.07 9.35E-06 9.30E-04 ± 6.10E-04 1.24E-01 5.00E-03 6.00E-02 ± 2.00E-02 2.23E-03 5.99E-03
  1. Heritability (±SE) estimates are shown for the 17 individual CpG units and their average. Significance p-values for heritability estimates are shown. Association β (±SE) values, their associated significance p-values, and the portion of total variance in methylation explained by age and sex are also shown.