Fatty acid binding protein 3 (fabp3) is associated with insulin, lipids and cardiovascular phenotypes of the metabolic syndrome through epigenetic modifications in a northern european family population

Table 3 Associations between MetS traits and methylation status of FABP3

MetS trait	CpG Site	β±SE	Var explained	Change attributable to methylation	P value
TC (mg/dl)	FABP3_AVG	0.17* ± 0.045	0.0240	6.60 ± 0.045	0.00028
BMED (nm)	FABP3_17/18	−0.15* ± 0.05	0.0210	−0.18 ± 0.051	0.00253
DBP (mmHg)	FABP3_13	−0.16* ± 0.049	0.0170	−1.65 ± 0.050	0.00129
SI (× 10-4/min/μU/ml)	FABP3_21/22	−0.16* ± 0.051	0.0160	−0.39 ± 0.051	0.00144

The traits or CpG units that showed any significant associations are presented. For each trait/CpG pair, β (±SE), total trait variance explained by the association (varexp), and the absolute change in that trait attributable to methylation of the specific CpG site are shown. *associations with confidence interval of 95%.

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