Figure 5

Correlation between the QRT-PCR findings and the MRI findings and immumohistochemical staining showing the expression of the proteins encoded by the DEGs of CMT (X200). The MRI of subjects #1, #2 and #3. Red and green circles indicate the cross sectional areas of the SCM with or without CMT, respectively. The red arrows indicate the lowest signal areas of CMT. (A). The correlation between the differences of MRI color intensities and the differences of expressions of 8 DEGs in the tissue with and without CMT for a total of 11 independent patients (B). Immunohistochemical staining shows significantly increased immuno-expression of ELN, ASPN and CHD3 (C).