Figure 4

The degree of disease annotation plotted against MeSHOP comparison score. The figure displays a heatmap depicting the number of drug-disease tuples for a disease annotation level (MeSH terms attached to the disease MeSHOP) on the x-axis and a MeSHOP comparison score on the y-axis. MeSHOP similarity scores were calculated using Euclidean Distance. The degree of disease annotation, measured as the total number of distinct MeSH terms associated with a disease, is highly inversely correlated (Pearson correlation score of -0.82) with the similarity score.