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Table 5 Associations of diplotypes.

From: Diplotyper: diplotype-based association analysis

Diplotypes Minor; Major Diplotype frequency Effect Standard error P value
b1_H12(AAT-or-GAC)/b1_OH12(*) b1_H12; b1_OH12 612/3064/3858 0.041 0.0044 9.09E-19
b1_H6(AAC-or-AGC)/b1_OH6(*) b1_OH6; b1_H6 617/3064/3853 0.040 0.0044 1.04E-18
b1_H6(AAC-or-AGC)/b1_H12(AAT-or-GAC) b1_H12; b1_H6 612/3059/3853 0.040 0.0044 1.28E-18
b1_H9(AAT)/b1_OH9(*) b1_H9; b1_OH9 346/2616/4572 0.036 0.0049 2.45E-12
b1_H7(AAC-or-AGC-or-GAC)/b1_OH7(*) b1_OH7; b1_H7 350/2618/4566 0.035 0.0049 2.73E-12
b1_H7(AAC-or-AGC-or-GAC)/b1_H9(AAT) b1_H9; b1_H7 346/2612/4566 0.036 0.0049 2.86E-12
b1_H6(AAC-or-AGC)/b1_H9(AAT) b1_H9; b1_H6 346/2375/3853 0.037 0.0052 4.58E-12
b1_H1(AAC)/b1_H12(AAT-or-GAC) b1_H12; b1_H1 612/1933/1498 0.039 0.0057 3.72E-11
b1_H12(AAT-or-GAC)/b1_H13(AGC) b1_H13; b1_H12 564/1126/612 -0.050 0.0075 5.64E-11
b1_H13(AGC)/b1_OH13(*) b1_H13; b1_OH13 564/2922/4048 -0.023 0.0047 6.72E-07
  1. Associations of diplotypes with HDL-C levels (the top 10 results in terms of P value).
  2. Effect sizes (mmol/l) shown are β-coefficients and measured as additive effects, which correspond to the average change in HDL-C levels when one major haplotype cluster is replaced with one minor haplotype cluster.