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Table 5 Associations of diplotypes.

From: Diplotyper: diplotype-based association analysis

Diplotypes

Minor; Major

Diplotype frequency

Effect

Standard error

P value

b1_H12(AAT-or-GAC)/b1_OH12(*)

b1_H12; b1_OH12

612/3064/3858

0.041

0.0044

9.09E-19

b1_H6(AAC-or-AGC)/b1_OH6(*)

b1_OH6; b1_H6

617/3064/3853

0.040

0.0044

1.04E-18

b1_H6(AAC-or-AGC)/b1_H12(AAT-or-GAC)

b1_H12; b1_H6

612/3059/3853

0.040

0.0044

1.28E-18

b1_H9(AAT)/b1_OH9(*)

b1_H9; b1_OH9

346/2616/4572

0.036

0.0049

2.45E-12

b1_H7(AAC-or-AGC-or-GAC)/b1_OH7(*)

b1_OH7; b1_H7

350/2618/4566

0.035

0.0049

2.73E-12

b1_H7(AAC-or-AGC-or-GAC)/b1_H9(AAT)

b1_H9; b1_H7

346/2612/4566

0.036

0.0049

2.86E-12

b1_H6(AAC-or-AGC)/b1_H9(AAT)

b1_H9; b1_H6

346/2375/3853

0.037

0.0052

4.58E-12

b1_H1(AAC)/b1_H12(AAT-or-GAC)

b1_H12; b1_H1

612/1933/1498

0.039

0.0057

3.72E-11

b1_H12(AAT-or-GAC)/b1_H13(AGC)

b1_H13; b1_H12

564/1126/612

-0.050

0.0075

5.64E-11

b1_H13(AGC)/b1_OH13(*)

b1_H13; b1_OH13

564/2922/4048

-0.023

0.0047

6.72E-07

  1. Associations of diplotypes with HDL-C levels (the top 10 results in terms of P value).
  2. Effect sizes (mmol/l) shown are β-coefficients and measured as additive effects, which correspond to the average change in HDL-C levels when one major haplotype cluster is replaced with one minor haplotype cluster.