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Table 5 Functional modules related to the drug-colorectal cancer associations

From: Inferring drug-disease associations from integration of chemical, genomic and phenotype data using network propagation

Database Functional modules p-value
BIOCARTA GSK3 pathway 7.29E-14
KEGG Endometrial cancer 2.30E-11
KEGG Colorectal cancer 4.32E-9
KEGG, BIOCARTA, REACTOME Toll like receptor pathway 5.79E-9
KEGG Prostate cancer 1.36E-6
BIOCARTA P53hypoxia pathway 1.93E-6
KEGG Lung cancer 2.30E-6
KEGG Glioma 5.82E-6
KEGG Renal cell carcinoma 8.40E-6
KEGG Melanoma 9.01E-6
KEGG Chronic myeloid leukemia 1.03E-5
KEGG VEGF signaling pathway 1.26E-5
KEGG Innate Immune System 1.29E-5
KEGG Fc epsilon RI signaling pathway 1.52E-5
REACTOME Regulation of ornithine decarboxylase (ODC) 4.28E-5
KEGG Pancreatic cancer 1.74E-4
KEGG Wnt signaling pathway 3.34E-4
GO Apoptosis 1.54E-3
KEGG Neurotrophin signaling pathway 1.62E-3