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Table 2 Top 10 DM loci obtained with LIMMA

From: Exploring the molecular causes of hepatitis B virus vaccination response: an approach with epigenomic and transcriptomic data

Locus Gene Mean β t-statistic P-value Adjusted p-value B-statistic
cg27427514 - 0.103 -5.541 6.96E-06 0.529 2.195
cg19938535 LRRC16A 0.668 4.980 3.15E-05 1.000 0.808
cg25548594 - 0.322 -4.717 6.39E-05 1.000 0.158
cg01821429 - 0.171 -4.697 6.75E-05 1.000 0.107
cg21899558 PRKAR1B 0.820 4.679 7.09E-05 1.000 0.063
cg01600516 ALOX12 0.690 4.376 1.60E-04 1.000 -0.688
cg26143874 - 0.815 4.252 2.23E-04 1.000 -0.991
cg15773974 - 0.629 4.167 2.81E-04 1.000 -1.201
cg01074767 C1RL; LOC283314 0.597 -4.046 3.87E-04 1.000 -1.495
cg03424554 WWP2 0.467 -3.990 4.49E-04 1.000 -1.633
  1. Column 1 contains the locus ID; Column 2 the gene symbol(s) to which the probe is annotated; Column 3 the average methylation level (β) across all samples; Column 4 moderated t-statistic with standard errors shrunken to a common value; Column 5 nominal p-value; Column 6 multiple testing corrected p-value; column 7 Bayesian odd ratio of DM. In the last column in bold are the odd ratios greater than 0, suggesting differential methylation.