Megabase regions enriched with methylation differences. Promoter MeDIP differences across chromosomes 16 (A), 17 (B) and X (C) and across two smaller genomic regions (D) and (E) are shown using images obtained from the UCSC Genome Browser. The top track depicts average differences of log abuse – log non-abuse. Each bar in the middle track identifies a significant difference. Bars above or below the horizontal line identify sites with higher or lower methylation in the abused group. The bottom track indicates relative gene abundance across the chromosome.