A genetic variant in the LDLRpromoter is responsible for part of the LDL-cholesterol variability in primary hypercholesterolemia

Table 4 Variables independently associated with LDL-cholesterol concentration by multivariate lineal regression analysis*

Variables	Standardized coefficient (β)	P	Adjusted R²
Men
Lipoprotein(a), mg/dL	0.190	< 0.001	0.039
LDLR g.3131C > T, yes/no	-0.179	< 0.001	0.070
Age, years	0.177	< 0.001	0.100
All study subjects
Age, years	0.236	< 0.001	0.054
Lipoprotein(a), mg/dL	0.172	< 0.001	0.083
LDLR g.3131C > T, yes/no	-0.146	< 0.001	0.103

*Variables allowed to enter the model were those with P values < 0.20 in the bivariate analysis.

ISSN: 1755-8794