Figure 5From: Whole-genome sequencing of matched primary and metastatic hepatocellular carcinomas Significantly altered pathway in primary tumor. Pathway analysis for primary tumor mutant genes identified significant genomic alteration in several cancer pathways, including (A) Wnt, (B) focal adhesion, (C) JAK-STAT and (D) cell cycle pathways. Alterations included somatic SNVs, Indels, CNAs and SVs. Alteration recurrence was referred as number of cases harboring a mutant gene. Alteration types were represented by different colours.Back to article page