Significantly altered pathway in primary tumor. Pathway analysis for primary tumor mutant genes identified significant genomic alteration in several cancer pathways, including (A) Wnt, (B) focal adhesion, (C) JAK-STAT and (D) cell cycle pathways. Alterations included somatic SNVs, Indels, CNAs and SVs. Alteration recurrence was referred as number of cases harboring a mutant gene. Alteration types were represented by different colours.