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Figure 5 | BMC Medical Genomics

Figure 5

From: Analytical validation of whole exome and whole genome sequencing for clinical applications

Figure 5

Precision vs. non-reference concordance (NRC) for WES (A) and WGS (B) SNVs (solid line) and Indels (dashed line) as a function of VQSR VQSLoD score relative to GIAB high confidence and all variant sets. Thick line is mean across all replicates; shaded region shows the standard deviation. Points show the PR at the VQSR PASSing threshold. VQSR is not applied in WES indels; points show PR for PASSing and all variants (both PASS and not-PASS).

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