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Table 3 CpG sites associated with overall survival following EOC (p < 10 -3 )

From: Methylation of leukocyte DNA and ovarian cancer: relationships with disease status and outcome

Probe Ch Position (bp) Nearest genes Location of nearest gene (bp)# Relation to Island^ Meta-Analysis* Batch 1 Batch 2 Batch 3
       HR P HR P HR P HR P
cg10276549 X 151143686 GABRE 151121596-151143151 Shore 0.95 5.8E-5 0.96 0.32 0.97 0.19 0.94 2.9E-4
cg06171242 6 24667490 ACOT13 24667263-24705297 Shore 1.10 4.4E-4 1.20 0.22 1.11 7.2E-3 1.02 0.87
TTRAP/TDP2 24650205-24667115
cg14360897 17 4843676 RNF167 4843630-4848517 Shore 1.22 5.9E-4 1.25 0.084 1.29 3.8E-3 1.13 0.20
SLC25A11 4840425-4843462
cg26802333 16 56716182 MT1X 56716382-56718108 Island 1.07 7.4E-4 1.11 0.044 1.07 1.2E-3 1.00 0.97
cg03729431 17 15848264 ADORA2B 15848231-15879210 Island 1.11 7.5E-4 0.97 0.85 1.12 5.8E-3 1.09 0.69
cg21858376 3 4534791 ITPR1 4535032-4889524 Island 1.12 7.9E-4 1.31 0.11 1.11 0.022 1.09 0.37
cg12003230 21 44899139 C21orf84/ 44881974-44898103   0.86 8.1E-4 0.82 0.022 0.85 8.9E-3 0.97 0.72
LINC00313
cg05026186 5 148520876 ABLIM3 148521054-148639999 Shore 0.96 9.3E-4 0.98 0.41 0.96 5.3E-3 0.96 0.071
  1. #Locations based on NCBI (http://www.ncbi.nlm.nih.gov), build 37.
  2. ^Shore CpG sites defined to be within +/- 2 kb from CpG island; Shelf CpG sites defined to be within +/- 2kb of CpG Shore.
  3. *All tests for heterogeneity of effects across the three batches were non-significant (p > 0.05); analysis adjusted for age at diagnosis, tumor stage, presence of ascites and volume of residual tumor following debulking surgery.