Figure 6

Heatmaps of the modules identified by Genomica tool, which compares gene lists of immune cells and diabetic association genes with demographic, clinical, laboratory and treatment features of patients ( P value ≤ 0.05, corrected by the false discovery rate - FDR ≤ 0.05. The four module maps presented list of genes (induced or repressed), identified by: A) Non-informative filters (DBF-MCL algorithm) in the basis of FDR ≤ 10%; B) Rank products analysis of T1D vs. GDM; C) Rank products analysis of T2D vs. GDM; D) Rank Products analysis of T1D vs. T2D. Abbreviations: MF - macrophages ; B1a and B1b - subsets of B lymphocytes; BFo - follicular B lymphocytes; BMz - marginal zone B lymphocytes; Treg - regulatory T lymphocytes; DC - dendritic cells ; CD4 and CD8 - subsets of T lymphocytes.