Figure 1

Global DNA methylation profiling in nasal epithelial cells (NECs) during Human Rhinovirus (HRV) infection. A. Analysis of CpG methylation within genome wide Alu elements in Mock and HRV infected NECs from Healthy and Asthmatics (Population 1, see Table 1). B. Change in Alu methylation in response to virus infection between Healthy and Asthmatics indicating that both disease status and virus infection influenced global DNA methylation in NECs. Mean ± SEM.