Influence of disease-status on loci-specific DNA methylation in nasal epithelial cells (NECs). A. Principal component analysis (PCA) of methylation microarray data set (389 probes/sample) revealed a clear separation between Healthy and Asthmatic NECs along PC1. B-C. Cluster analysis of genomic methylation loci revealed patterns characterizing Healthy (B) and Asthma (C) NECs (e.g. Mitotic arrest deficient like-1(yeast)-MAD1L1 for Healthy and Cadherin member 28-CDH28 for Asthma), which were not influenced by virus infection. M-mock, RV- HRV infected.