Figure 6From: Kinome and mRNA expression profiling of high-grade osteosarcoma cell lines implies Akt signaling as possible target for therapy Proliferation of osteosarcoma cell lines was inhibited with different concentrations of MK-2206, for 120 hours. NALM-6, U-2 OS, and HOS showed a dose-dependent inhibition, while 143B did not respond.Back to article page