Novel application of multi-stimuli network inference to synovial fibroblasts of rheumatoid arthritis patients

BMC Medical Genomics

Table 4 GO analysis and the top 10 GO terms resulting from GO analysis

TermID	Category	Count	Size	p-value	Term
GO:0051216	BP	24	134	1.02e-15	Cartilage development
GO:0034097	BP	101	440	1.14e-15	Response to cytokine stimulus
GO:0071345	BP	84	343	6.59e-15	Cellular response to cytokine stimulus
GO:0019221	BP	71	281	1.68e-13	Cytokine-mediated signaling pathway
GO:0042127	BP	173	1007	5.77e-13	Regulation of cell proliferation
GO:0061035	BP	11	37	5.92e-13	Regulation of cartilage development
GO:0044249	BP	557	4336	6.16e-13	Cellular biosynthetic process
GO:0034645	BP	464	3483	7.49e-13	Cellular macromolecule biosynthetic process
GO:0070887	BP	213	1324	7.68e-13	Cellular response to chemical stimulus
GO:0048522	BP	369	2649	1.58e-12	Positive regulation of cellular process

The GO term ‘cartilage development’ was the most significant term with a p-value of 1.02e^-15. The GO term ‘regulation of cartilage development’ (GO: 0061035) was also listed with a p-value of 5.92e^-13, containing a subset of the genes of the GO term ‘cartilage development’.

ISSN: 1755-8794