Figure 5

Immune cell infiltration in placental tissues from healthy group, mild ICP, and severe ICP. (A) Representative images of immunohistochemistry staining for the leukocyte marker CD45 in placental tissues from healthy group, mild ICP, and severe ICP (10 pregnancies per group). Brown staining (arrows) indicates reactivity. Scale bars represent 100 μm. (B) Quantification of leukocytes (CD45 positive), T cell (CD3 positive) and B cell (CD19 positive) in placental tissues from healthy group, mild ICP, and severe ICP (10 pregnancies per group). Data are presented as mean ± s.d. (n = 10). **p < 0.01; ***p < 0.001.