Functional characterization of breast cancer using pathway profiles

BMC Medical Genomics

Table 3 Overlaps of common enriched pathways across three data sets

Pathway	Pathway category	Reference^a
Glycolysis/Gluconeogenesis	Carbohydrate metabolism	[82]
Sphingolipid metabolism	Lipid metabolism	[83]
Purine metabolism	Nucleotide metabolism	[84]
Pyrimidine metabolism	Nucleotide metabolism	[85]
Arginine and proline metabolism	Amino acid metabolism	[86]
Tyrosine metabolism	Amino acid metabolism	[87]
Phenylalanine metabolism	Amino acid metabolism	[88]
One carbon pool by folate	Metabolism of cofactors and vitamins	[89]
Fanconi anemia pathway	Replication and repair	[90]
PI3K-Akt signaling pathway	Signal transduction	[91]
Regulation of actin cytoskeleton	Cell motility	[92]
Focal adhesion	Cell communication	[93]
Adipocytokine signaling pathway	Endocrine system	[94]
Progesterone-mediated oocyte maturation	Endocrine system	-
Axon guidance	Development	[95]

^aReference shows association between a given pathway and breast cancer or other cancers.

ISSN: 1755-8794