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Table 4 HER2+ specific pathways

From: Functional characterization of breast cancer using pathway profiles

Pathway

Pathway category

Referencea

Tryptophan metabolism

Amino acid metabolism

-

Terpenoid backbone biosynthesis

Metabolism of terpenoids and polyketides

-

Drug metabolism - cytochrome P450

Xenobiotics biodegradation and metabolism

-

mTOR signaling pathway

Signal transduction

[63]

Serotonergic synapse

Nervous system

-

Long-term depression

Nervous system

-

Circadian rhythm

Environmental adaptation

[64]

  1. aReference shows association between a given pathway and the HER2+ subtype.