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Table 3 Changed mRNAs in rat ARDS

From: MicroRNA and mRNA expression profiling in rat acute respiratory distress syndrome

Gene Full name Fold change q-value
Mt3 Metallothionein 3 43.49 <0.05
S100a9 S100 calcium binding protein A9 (calgranulin B) 6.81 <0.05
Prdx6 Peroxiredoxin-6 5.89 <0.05
TIMP1 Metalloproteinase inhibitor 1 5.79 <0.05
Ccl2 Chemokine (C-C motif) ligand 2 3.90 <0.05
Sod2 Superoxide dismutase 2, mitochondrial 2.98 <0.05
Lcn2 Lipocalin 2 2.59 <0.05
Ifrd1 Interferon-related developmental regulator 1 2.16 <0.05
Apc Adenomatosis polyposis coli 2.02 <0.05
Ebf1 Early B-cell factor 1 2.00 <0.05
Mt2a metallothionein-2 and metallothionein-1 genes 2.00 <0.05
Cyb5 Cytochrome b5 0.52 <0.05
L20990 T cell receptor 0.51 <0.05
Serpinh1 Serine (or cysteine) proteinase inhibitor, clade H, member 1 0.5 <0.05
S100a4 S100 calcium-binding protein A4 0.49 <0.05
Eif2ak1 Eukaryotic translation initiation factor 2-alpha kinase 1 0.49 <0.05
Fbln5 Fibulin 5 0.48 <0.05
Aco2 Aconitase 2, mitochondrial 0.48 <0.05
Akr1b4 Aldo-keto reductase family 1, member B4 (aldose reductase) 0.47 <0.05
Lct Lactase-phlorizinhydrolaseLactasePhlorizin hydrolase 0.47 <0.05
Slc25a11 Solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), Member 11 0.47 <0.05
Ramp2 Receptor (calcitonin) activity modifying protein 2 0.47 <0.05
G8 G8 gene 0.46 <0.05
Acaa2 Acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase) 0.43 <0.05
Gabrb1 Gamma-aminobutyric acid (GABA-A) receptor, subunit beta 1 0.43 <0.05
M13801 Ig germline alpha H-chain C-region gene 0.42 <0.05
Septin 5 Septin 5 0.4 <0.05
Mdh1 Malate dehydrogenase 1, NAD (soluble) 0.39 <0.05
Psma4 Proteasome (prosome, macropain) subunit, alpha type 4 0.39 <0.05
Alad Aminolevulinate, delta-, dehydratase 0.38 <0.05
Igfbp6 Insulin-like growth factor binding protein 6 0.37 <0.05
Ces3 Carboxylesterase 3 0.35 <0.05
U06230 protein S mRNA 0.31 <0.05
Fgfr4 Fibroblast growth factor receptor subtype 4 (FGFR4) mRNA 0.27 <0.05
Lim2 Lens intrinsic membrane protein 2 0.24 <0.05
Tspan8 Tetraspanin 8 0.24 <0.05
Gnrh1 Progonadoliberin-1Gonadoliberin-1Prolactin release-inhibiting factor 1 0.08 <0.05
  1. A list of increased and decreased mRNAs in rat ARDS (n = 4 animals) when compared to normal lung samples (n = 4 animals) with a q value of < 0.05 (SAM) and a fold change of ≥ 2.