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Figure 1 | BMC Medical Genomics

Figure 1

From: MutaCYP: Classification of missense mutations in human cytochromes P450

Figure 1

Distribution of the features used in the final prediction model over benign and deleterious mutations. A. Abs_dSS – absolute difference between similarity scores of wild type amino acid and mutation for a given position. B. ss_Abs_dSize – absolute difference between sizes of wild type amino acid and mutation weighted by the difference of the corresponding similarity scores. C. zsEntropy21 – Z-score for Shannon entropy at a given position based on a window of 21 neighboring amino acids. D. predRSA – predicted RSA. E. varPredRSA21 – variance of predicted RSA for the window of 21 neighboring amino acids. Whiskers indicate minimal and maximal values of a given feature.

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