BMC Medical Genomics

Table 5 Performance of the evaluated methods on the blind set (BS292)

From: MutaCYP: Classification of missense mutations in human cytochromes P450

Method^a	Predicted mutation status		Correlation,r
Method^a	Benign	Deleterious	PolyPhen-2 HumVar	PolyPhen-2 HumDiv	SIFT
MutaCYP	115	177	0.48	0.48	0.34
PolyPhen-2 HumVar	170	122		0.96	0.47
PolyPhen-2 HumDiv	162	130			0.48
SIFT	161	124

^aSIFT predictions miss 7 mutations.

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