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Table 5 Performance of the evaluated methods on the blind set (BS292)

From: MutaCYP: Classification of missense mutations in human cytochromes P450

Methoda

Predicted mutation status

Correlation,r

Benign

Deleterious

PolyPhen-2 HumVar

PolyPhen-2 HumDiv

SIFT

MutaCYP

115

177

0.48

0.48

0.34

PolyPhen-2 HumVar

170

122

 

0.96

0.47

PolyPhen-2 HumDiv

162

130

  

0.48

SIFT

161

124

   
  1. aSIFT predictions miss 7 mutations.
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BMC Medical Genomics

ISSN: 1755-8794

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