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Table 1 Baseline characteristics of North American subjects included in the study

From: Integrated genome-wide association, coexpression network, and expression single nucleotide polymorphism analysis identifies novel pathway in allergic rhinitis

 

Studya

 

CHS

CAMP

CAG/CSGA/SARP

GALA1

MCCAS

GRAAD

SAPPHIRE

Number

2881

384

283

521

476

809

279

Age (years)

8.3 (5.2-14.3)

8.8 (5.2-13.2)

27.3 (6.0-81.0)

14.8 (8.0-40.0)

9.0 (5.0-17.0)

40.0 (14.0-84.0)

30.3 (12.0-56.0)

Female

1344 (47%)

142 (37%)

150 (53%)

230 (44%)

198 (42%)

474 (59%)

219 (78%)

Race

       

European American

1552 (54%)

384 (100%)

98 (35%)

    

Latino

1329 (46%)

  

521 (100%)

476 (100%)

  

African American/African Caribbean

  

185 (65%)

  

809 (100%)

279 (100%)

Allergic Rhinitis

1096 (38%)

199 (52%)

245 (87%)

434 (83%)

250 (53%)

377 (47%)

111 (40%)

Asthma

1206 (42%)

384 (100%)

283 (100%)

521 (100%)

476 (100%)

228 (28%)

148 (53%)

Genotyping platformb

550 K, 610 K

550 K

1Mv1

6.0

550 K

650 K

6.0

  1. Values are mean (range) or number (percent).
  2. aCHS = Children’s Health Study, CAMP = Childhood Asthma Management Program, CAG = Chicago Asthma Genetics Study, CSGA = Collaborative Studies on the Genetics of Asthma, SARP = Severe Asthma Research Program, GALA1 = Genetics of Asthma in Latinos, MCCAS = Mexico City Childhood Asthma Study, GRAAD = Genomic Research on Asthma in the African Diaspora and Barbados, SAPPHIRE = Study of Asthma Phenotypes and Pharmacogenomic Interactions by Race-Ethnicity. Detailed descriptions of the individual studies have been previously described [25].
  3. bThe Illumina arrays used were the 1Mv1, 550 k, 610 k and 650 k. The Affymetrix arrays used were the 500 k and 6.0.