Table 2 Overview of the most significantly overrepresented KEGG pathways and GO terms associated with the modules detected using WGCNA
WGCNA module | KEGG pathway or GO-term | Frequency in module | Number of genes in term | Padj |
|---|---|---|---|---|
Blue | KEGG: Osteoclast differentiation | 12 | 52 | 1.40E-07 |
| Â | KEGG: Natural Killer cel mediated cytotoxity | 8 | 34 | 3.76E-05 |
| Â | KEGG: B cell receptor signaling pathway | 7 | 29 | 7.24E-05 |
| Â | GO: Immune system response | 39 | 516 | 5.57E-11 |
| Â | GO: Cell activation | 26 | 217 | 2.53E-10 |
| Â | GO: Regulation of immune system response | 28 | 82 | 1.22E-09 |
Black | GO: Extracellular region | 40 | 382 | 5.53E-06 |
| Â | GO: Extracellular matrix | 21 | 121 | 3.61E-05 |
| Â | GO: Proteinaceous extracellular matrix | 19 | 97 | 3.61E-05 |
Lightyellow | GO: Nucleolus | 8 | 124 | 1.30E-02 |
| Â | GO: Ribosome biogenesis | 4 | 18 | 3.40E-02 |
| Â | GO: Nuclear par | 12 | 437 | 3.40E-02 |