Figure 2

WITHIN-STUDY, Dataset I concordance of PTBP1-KD associated mechanisms unveiled by N-of-1- pathways and FET Enrichment in RNA-Seq neuronal cell line. The Venn Diagrams correspond to the overlap of deregulated mechanisms, GO-BP terms (left panel) and KEGG pathways (right panel) found between N-of-1-pathways (at different cutoff, Bonf. ≤ 1%, Bonf. ≤ 5% and FDR ≤ 5%) and FET Enrichment method (FDR≤5%). The Odds Ratios (OR) and p-values are shown below each Venn Diagram. GSEA is not represented, as it cannot be computed with a single paired sample.