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Table 3 Concordance of regulated mechanisms by PTBP1 across three cell lines (neuronal, breast cancer and ovarian cell lines) discovered by N-of-1-pathways.

From: Concordance of deregulated mechanisms unveiled in underpowered experiments: PTBP1 knockdown case study

GO-BP Classes GO-BP Overlap GO-BP ITS ≥ 0.7
RNA splicing/RNA processing GO:0008380 RNA splicing GO:0000398 mRNA splicing, via spliceosome
  GO:0006397 mRNA processing GO:0000375 RNA splicing, via transesterification reactions
    GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
    GO:0016071 mRNA metabolic process
    GO:0034470 ncRNA processing
    GO:0006364 rRNA processing
Cell cycle/cell division GO:0007067 mitosis GO:0000279 M phase
  GO:0051301 cell division GO:0000216 M/G1 transition of mitotic cell cycle
  GO:0000280 nuclear division GO:0000082 G1/S transition of mitotic cell cycle
  GO:0000087 M phase of mitotic cell cycle GO:0000086 G2/M transition of mitotic cell cycle
  GO:0051325 interphase GO:0000236 mitotic prometaphase
  GO:0051329 interphase of mitotic cell cycle GO:0051320 S phase
  GO:0006260 DNA replication GO:0000084 S phase of mitotic cell cycle
  GO:0007059 chromosome segregation GO:0000819 sister chromatid segregation
  GO:0071156 regulation of cell cycle arrest GO:0006261 DNA-dependent DNA replication
  GO:0010564 regulation of cell cycle process GO:0000070 mitotic sister chromatid segregation
  GO:0000075 cell cycle checkpoint GO:0007093 mitotic cell cycle checkpoint
  GO:0000226 microtubule cytoskeleton organization GO:0045786 negative regulation of cell cycle
  GO:0007017 microtubule-based process GO:0010948 negative regulation of cell cycle process
  GO:0048285 organelle fission GO:0007346 regulation of mitotic cell cycle
    GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
    GO:0031023 microtuble organizing center organization
    GO:0051327 M phase of meitic cell cycle
    GO:0007051 spindle organization
    GO:0007126 meiosis
    GO:0051321 meiotic cell cycle
Chromatin modifications/ remodeling    GO:0016568 chromatin modification
    GO:0006325 chromatin organization
    GO:0016569 covalent chromatin modification
    GO:0016570 histone modification
    GO:0051052 regulation of DNA metabolic process
DNA repair GO:0006310 DNA recombination GO:0006974 response to DNA damage stimulus
  GO:0006281 DNA repair GO:0006302 double-strand break repair
Neuronal process    GO:0031644 regulation of neurological system process
    GO:0007268 synaptic transmission
    GO:0050804 regulation of synaptic transmission
    GO:0051969 regulation of transmission of nerve impulse
Others    GO:0007600 sensory perception