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Table 4 Hub genes (degree of nodes ≥ 10) in two-way interactions of WTCCC-BD

From: IGENT: efficient entropy based algorithm for genome-wide gene-gene interaction analysis

Hub gene

degree

location

SNP(s)

Referencea

B3GALT5

115

21q22.2b

rs980184

[25]

LOC442261

98

6q23.2d

rs4896044

 

PI15

32

8q21.11b

rs2954873

[26]

LOC390730

26

16q12.2a

rs7188309 rs11640993 rs8056052

rs2192859 rs1344484 rs10521275 rs11647459 rs2387823

[19]

PHF20

24

20q11.23a

rs6060710

 

TLE4

13

9q21.31b

rs914715 rs11138278

[27]

DPP10

12

2q14.1b

rs11123306 rs708647 rs1375144 rs6741692

[28, 19]

AKAP10

10

17p11.2d

rs203466 rs203457 rs119672 rs2108978

[29]

CHST2

10

3q23d

rs4683457

[30]

  1. a. Reference is literature related with bipolar disorder.