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Table 10 The performances of various protein complex detection algorithms on PPI datasets using the MIPS gold standard

From: Integrating PPI datasets with the PPI data from biomedical literature for protein complex detection

   Collins Gavin Krogan-core Krogan-extended BioGRID Avg.Δ
C
O
A
C
H
Accuracy 0.4384 0.3706 0.3164 0.3168 0.4120  
  Accuracy(-0.6) 0.4325 0.3783 0.3391 0.3386 0.4164  
  Δ(-0.6) -1.34% 2.08% 7.17% 6.88% 1.07% 3.17%
  Accuracy(0)      0.4196  
  Δ(0)      1.84%  
  MMR 0.3390 0.3164 0.2630 0.2719 0.3221  
  MMR(-0.6) 0.3671 0.3368 0.3202 0.3372 0.3287  
  Δ(-0.6) 8.29% 6.45% 21.75% 24.02% 2.05% 12.51%
  MMR(0)      0.3296  
  Δ(0)      2.33%  
C
M
C
Accuracy 0.382 0.3329 0.2945 0.2956 0.3000  
  Accuracy(-0.6) 0.3922 0.3371 0.3209 0.317 0.3056  
  Δ(-0.6) 2.67% 1.26% 8.96% 7.24% 1.87% 4.4%
  Accuracy(0)      0.3085  
  Δ(0)      2.83%  
  MMR 0.2593 0.2859 0.1821 0.2039 0.0680  
  MMR(-0.6) 0.2935 0.3118 0.2527 0.2752 0.0702  
  Δ(-0.6) 13.19% 9.06% 38.77% 34.97% 3.24% 19.85%
  MMR(0)      0.0719  
  Δ(0)      5.74%  
R
R
W
Accuracy 0.3382 0.3339 0.2886 0.2975 0.3409  
  Accuracy(-0.6) 0.3433 0.3387 0.3095 0.3139 0.3361  
  Δ(-0.6) 1.51% 1.44% 7.24% 5.51% -1.41% 2.86%
  Accuracy(0)      0.3447  
  Δ(0)      1.11%  
  MMR 0.3148 0.2959 0.2479 0.2549 0.2759  
  MMR(-0.6) 0.3198 0.3058 0.2854 0.2787 0.2527  
  Δ(-0.6) 1.59% 3.35% 15.13% 9.34% -8.41% 4.2%
  MMR(0)      0.2794  
  Δ(0)      1.27%  
  1. MMR(-0.6) denotes the MMR value when with the threshold -0.6; Δ(-0.6) denotes the MMR improvement when with the threshold -0.6 over that on the original datasets. MMR(0) denotes the MMR value when with the threshold 0; Δ(0) denotes the MMR improvement when with the threshold 0 over that on the original datasets.