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Table 11 The performances of various protein complex detection algorithms on PPI datasets using the SGD gold standard

From: Integrating PPI datasets with the PPI data from biomedical literature for protein complex detection

   Collins Gavin Krogan-core Krogan-extended BioGRID Avg.Δ
C
O
A
C
H
Accuracy 0.4930 0.5042 0.4515 0.4519 0.4750  
  Accuracy(-0.6) 0.4937 0.5085 0.4804 0.4852 0.4766  
  Δ(-0.6) 0.14% 0.85% 6.40% 7.37% 0.34% 3.02%
  Accuracy(0)      0.4779  
  Δ(0)      0.61%  
  MMR 0.2747 0.2614 0.2466 0.2538 0.3000  
  MMR(-0.6) 0.3056 0.2804 0.3000 0.3076 0.3020  
  Δ(-0.6) 11.25% 7.27% 21.65% 21.20% 0.67% 12.41%
  MMR(0)      0.2993  
  Δ(0)      -0.23%  
C
M
C
Accuracy 0.4635 0.4518 0.4179 0.4393 0.3203  
  Accuracy(-0.6) 0.4819 0.4587 0.4579 0.4746 0.3159  
  Δ(-0.6) 3.97% 1.53% 9.57% 8.04% -1.37% 4.35%
  Accuracy(0)      0.3283  
  Δ(0)      2.50%  
  MMR 0.2006 0.2378 0.1552 0.1724 0.0583  
  MMR(-0.6) 0.2273 0.2545 0.2135 0.2262 0.0518  
  Δ(-0.6) 13.31% 7.02% 37.56% 31.21% -11.15% 15.59%
  MMR(0)      0.0629  
  Δ(0)      7.89%  
R
R
W
Accuracy 0.5022 0.498 0.4676 0.469 0.5188  
  Accuracy(-0.6) 0.5098 0.5009 0.4855 0.4893 0.5062  
  Δ(-0.6) 1.51% 0.58% 3.83% 4.33% -2.43% 1.56%
  Accuracy(0)      0.528  
  Δ(0)      1.77%  
  MMR 0.2763 0.2636 0.2414 0.2476 0.2681  
  MMR(-0.6) 0.2901 0.2698 0.2771 0.2773 0.2550  
  Δ(-0.6) 4.99% 2.35% 14.79% 12.00% -4.89% 5.85%
  MMR(0)      0.2822  
  Δ(0)      5.26%