Table 2 Top 20 candidate disease-related genes identified by PageRank method with significant analysis from PIN, TSN, WPIN, WTSN, for Leukemia, respectively.
WTSN | WPIN | TSN | PIN | ||||
|---|---|---|---|---|---|---|---|
Genes | In GeneSigDB | Genes | In GeneSigDB | Genes | In GeneSigDB | Genes | In GeneSigDB |
ABL1 | yes | ESR1 | yes | ESR1 | yes | ESR1 | yes |
CDKN1A | yes | ABL1 | yes | ABL1 | yes | ABL1 | yes |
MLH1 | yes | CDKN1A | yes | MLH1 | yes | RB1 | yes |
MGMT | yes | CCND1 | yes | RB1 | yes | CDKN1A | yes |
LMNA | yes | CDKN2A | yes | CDKN1A | yes | RARA | yes |
NR0B2 | yes | MLH1 | yes | CDKN2A | yes | MLH1 | yes |
CHFR | yes | PARK2 | no | PTPN6 | yes | CDH1 | yes |
DIABLO | yes | MME | yes | SYK | yes | PTPN6 | yes |
CEBPD | yes | MYOD1 | yes | PTEN | yes | CDKN2A | yes |
DAPK1 | yes | LMNA | yes | MGMT | yes | PARK2 | no |
GRB2 | yes | NR0B2 | yes | HCK | yes | SYK | yes |
ACTB | yes | MGMT | yes | THBS1 | yes | CCND1 | yes |
HDAC1 | yes | APAF1 | yes | LMNA | yes | TP73 | yes |
HSP90AA1 | yes | PGR | yes | NR0B2 | yes | MYOD1 | yes |
PAX6 | yes | AHR | yes | UBC | yes | PTEN | yes |
FYN | yes | DAPK1 | yes | CHFR | yes | LMNA | yes |
EEF1A1 | yes | PAX6 | yes | DAPK1 | yes | THBS1 | yes |
JAK1 | yes | CIITA | yes | GSTP1 | yes | MGMT | yes |
CRKL | yes | CHFR | yes | RARB | yes | HCK | yes |
CCNB1 | yes | HIC1 | yes | DIABLO | no | NR0B2 | yes |