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Table 6 Top amino acid physicochemical properties identified using variable importance feature in random forest.

From: Predicting host tropism of influenza A virus proteins using random forest

Model

Amino acid property

AAIndex ID and reference [29]

HA

Charge

KLEP940101 [53]

 

Normalized van der Waals volume

FAUJ880103 [54]

 

Polarizability

CHAM820101 [55]

NA

Solvent accessibility

JANJ780102/JAN780103 [56]

 

Polarity

GRAR740102 [57]

NS1

Charge

KLEP940101 [53]

PA

Hydrophobicity

ENGD860101 [58]

 

Polarity

GRAR740102 [57]

PB1

Solvent accessibility

JANJ780102/JAN780103 [56]

PB2

Charge

KLEP940101 [53]

 

Solvent accessibility

JANJ780102/JAN780103 [56]